San Francisco (0-0) at Indianapolis (0-0), Sunday, 1:00 p.m. EDT, Sports.com Line: San Francisco -3 Total: 34
The 49ers and Colts will both make their preseason debuts Sunday at Lucas Oil Stadium. This is the first time in both teams’ histories that they will square off in the preseason. Vegas Odds
These two teams last faced each other during the regular season in Week 8 last season in Indianapolis. The Colts defeated the 49ers 18-14, rallying from a 14-9 halftime deficit. Joseph Addai hit Reggie Wayne with a 22-yd TD pass in the fourth quarter to give the Colts the lead for good. Peyton Manning threw for 347 yards, but it was the only full game in 2009 in which Manning failed to toss a TD pass.
Both teams are anticipating successful seasons in 2010. The Colts (14-2 in 2009) are hoping that they can continue a trend that has seen them win 12 or more games for seven straight seasons, while the 49ers (8-8 in 2009) are looking to reach the postseason for the first time since 2002. Betting Lines
As usual in the first preseason game for each team, the starters will likely get one or two series before the backups come in. Curtis Painter, who completed less than 30 percent (8-28) of his passes his rookie season, and second-year QB Tom Brandstater will get the majority of the time under center for the Colts. Free-agent acquisition David Carr and Nate Davis will get the majority of the snaps for the 49ers after Alex Smith departs. Football Odds
Since 2005, the Colts are an awful 4-18 in the preseason due primarily to the fact that Manning hardly plays. This is reason enough to take San Francisco giving the points.