Minnesota (1-0) at San Francisco (1-0), Sunday, 8:00 p.m. EDT Sports.com Line: San Francisco -3.5 Total: 35
The biggest question in San Francisco on Sunday night won’t have anything to do with the 49ers; it’ll focus entirely on who is under center for the Vikings. The summer drama that is Brett Favre is quickly becoming an August tradition, and Favre is now back with the Vikings. Of course, the way Sage Rosenfels started the preseason, there may be no need for Favre. Rosenfels was 23-34 for 310 yards and three touchdowns in Minnesota’s 28-7 win over St. Louis. The Vikings defense was equally as impressive, only allowing the Rams only 150 yards of offense. Odds

The 49ers opened the preseason in grand style with a 37-17 rout of the Colts in Indianapolis. David Carr was solid in relief of Alex Smith, connecting on 9-of-11 attempts for 98 yards and a TD. Rookie Anthony Dixon handled the load on the ground, rushing 21 times for 100 yards. The 49ers will have to take better care of the ball this week. Smith threw an INT and the team fumbled four times (losing three) vs. Indy. Scores

After the strong defensive effort against St. Louis, the FoxSheets like Minnesota here:

Play On – Underdogs of 3.5 to 10 points (MINNESOTA) – after allowing 75 or less rushing yards last game. (27-8 over the last 10 seasons.) (77.1%, +18.2 units. Rating = 2*). Las Vegas Odds