| 1:00 PM EST |
| 337 DENVER BRONCOS | -4 -08 | -5.5 / -6 / -6.5 | -6 | -250 | | 44 Over 39 0 |
| 338 KANSAS CITY CHIEFS | 37.5 | 38.5 / 39 / 39.5 | 39 | +210 | | 13 final 0 |
| DEN-WR-Royal and RB-Moreno both QuestionableKC-WR-Bowe-OUT |
|
| 1:00 PM EST |
| 339 OAKLAND RAIDERS | 37 | | 37 | +890 | | 27 Over 37 0 |
| 340 PITTSBURGH STEELERS | -14 -04 | -14.5 / -14.5 -05 / -14.5 | -15 | -1150 | | 24 final 0 |
| OAK-WR-Walker-QuestionablePIT-QB-Roethlisberger-Will StartPIT-S-Polamalu-OUT |
|
| 1:00 PM EST |
| 341 HOUSTON TEXANS | 46.5 | -2 / -1.5 / -1 | -1.5 | -130 | | 18 Under 47.5 0 |
| 342 JACKSONVILLE JAGUARS | -1 EVEN | 46.5 / 47 | 47.5 | +110 | | 23 final 0 |
| JAC-RB-Jones-Drew-Probable |
|
| 1:00 PM EST |
| 343 TENNESSEE TITANS | 47 | 47 / 46 / 46.5 | 47 | +200 | | 17 Under 47 0 |
| 344 INDIANAPOLIS COLTS | -7 | -6.5 / -6.5 -05 / -6.5 | -6 | -240 | | 27 final 0 |
| TEN-WR-Gage-QuestionableIND-DE-Freeney-QuestionableIND-WR-Gonzalez-OUT |
|
| 1:00 PM EST |
| 345 PHILADELPHIA EAGLES | -6 EVEN | -5.5 / -5 / -4.5 | -4 | -210 | | 34 Under 43.5 0 |
| 346 ATLANTA FALCONS | 44 | 44 | 43.5 | +175 | | 7 final 0 |
| PHI-RB-Westbrook-OUT; WRs-Jackson-OUT, WR-Curtis-QuestionableATL-QB-Ryan-Out; RB-Turner-Doubtful; WR-Finneran-Doubtful |
|
| 1:00 PM EST |
| 347 DETROIT LIONS | 42 | 42u10 / 42 / 42u10 | 42 | +600 | | 13 Under 42 0 |
| 348 CINCINNATI BENGALS | -13 -04 | -13 / -13 -05 / -13 | -13.5 | -800 | | 23 final 0 |
| DET-TE-Pettigrew-IRCIN-RB-Benson-Probable, WR-Coles-Questionable |
|
| 1:00 PM EST |
| 349 NEW ORLEANS SAINTS | -9.5 -04 | -9.5 / -9 / -8.5 | -8 | -420 | | 33 Over 47 0 |
| 350 WASHINGTON REDSKINS | 47.5 | 47.5 | 47 | +330 | | 30 final 0 |
| NO-WR-Moore-OUT, RB-Bush-DoubtfulWAS-DL-Haynesworth-Questionable, RB-Portis-Doubtful; QB-Campbell-Probable |
|
| 1:00 PM EST |
| 351 TAMPA BAY BUCCANEERS | 42o07 | 41.5 / 41 / 40.5 | 40 | +165 | | 6 Under 40 0 |
| 352 CAROLINA PANTHERS | -6.5 -04 | -5 / -4.5 / -4 | -3.5 | -190 | | 16 final 0 |
| TB-WR-Clayton-OUTCAR-QB-Delhomme-Doubtful, QB-Matt Moore expected to start, RB-Williams-Doubtful |
|
| 1:00 PM EST |
| 353 ST. LOUIS RAMS | 41 | 41 / 41o12 / 41o11 | 41 | +360 | | 9 Under 41 0 |
| 354 CHICAGO BEARS | -9 +03 | -9 -05 / -9.5 -05 / -9.5 | -9 | -460 | | 17 final 0 |
| STL-QB-Bulger-OUT, RB-Jackson-ProbableCHI-TE-Clark, CB-Tillman-both Questionable, OT-Pace, LB-Briggs-both OUT |
|
| 4:05 PM EST |
| 355 SAN DIEGO CHARGERS | -13 +11 | -13.5 / -13.5 -05 / -13.5 | -14 | -800 | | 30 Over 42.5 0 |
| 356 CLEVELAND BROWNS | 43 | 43 / 42.5 / 43 | 42.5 | +600 | | 23 final 0 |
| SD-LB-Merriman-QuestionableCLE-TE-Royal-Questionable, RB-Lewis-OUT (IR) |
|
| 4:15 PM EST |
| 357 SAN FRANCISCO 49ERS | 41 | +1 EVEN / -1 / -1 -15 | -1 | -106 | | 17 Under 41.5 0 |
| 358 SEATTLE SEAHAWKS | -1 EVEN | 41 | 41.5 | -104 | | 20 final 0 |
| SF-WRs-Battle, Bruce-both QuestionableSEA-RB-J.Jones-Probable |
|
| 8:20 PM EST |
| 359 MINNESOTA VIKINGS | -4 -04 | -3.5 -05 / -3 -15 / -3 -20 | -3 -30 | -190 | | 17 Under 48 0 |
| 360 ARIZONA CARDINALS | 48 | 48.5 / 49 / 48.5 | 48 | +165 | | 30 final 0 |
| NBCARZ-QB-Warner-Probable |
|
| 4:15 PM EST |
| 361 DALLAS COWBOYS | 45o09 | -2.5 / -2 / -1.5 | -1 | -130 | | 24 Over 45.5 0 |
| 362 NEW YORK GIANTS | -1 -06 | 45u10 / 45u06 / 45 | 45.5 | +110 | | 31 final 0 |
| NYG-QB-Manning-Probable, RB-Bradshaw-Probable, WR-Manningham-Questionable, RB-Ware-OUT |
|
| 1:00 PM EST |
| 363 NEW ENGLAND PATRIOTS | -5 -04 | -4 / -4 -15 / -4.5 | -5 | -240 | | 21 Under 46.5 0 |
| 364 MIAMI DOLPHINS | 46o08 | 45 / 45.5 / 46 | 46.5 | +200 | | 22 final 0 |
| NE-RB-Taylor-Questionable; WR-Edelman-OUT, QB-Brady-ProbableMIA-RB-Brown-OUT; MIA-RB-R.Williams-Probable; LB-Porter-Questionable |
|
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