By ROB MAADDI
AP Sports Writer

PHILADELPHIA(AP) -- Without Donovan McNabb, the Philadelphia
Eagles tried everything they could on offense. Drew Brees and
the New Orleans Saints stuck to what they do best.

Brees tossed three more touchdown passes Sunday, helping the
Saints beat Philadelphia 48-22.

Brees had six TD passes last week as the Saints (2-0) routed
Detroit 45-27. He picked up where he left off, picking apart
Philadelphia's secondary and completing 25 of 34 passes for 311
yards and one interception.

"If you look at our skill group, each game no guy ever knows
who's day it's gonna be," Brees said. "Each guy knows it's their
job to open things up for everyone else."

Making his first NFL start for an injured McNabb, Kevin Kolb
threw for 391 yards and two TDs, including a 71-yard scoring
pass to DeSean Jackson. Kolb also threw three interceptions,
though, including one returned 97 yards for a TD by Darren
Sharper in the final minute.

"I've got to cut those turnovers out," Kolb said. "I know better
than that. I will do it."

McNabb sat out with a cracked rib. With the five-time Pro Bowl
QB in street clothes, the Eagles (1-1) showed off their
creativity on offense.

Coach Andy Reid and offensive coordinator Marty Mornhinweg used
several variations of the wildcat formation with three different
players taking snaps. Both tackles were split wide one time with
only three linemen blocking. Kolb threw an incomplete pass on a
reverse flea flicker and Brian Westbrook had an incompletion.

It could get even wackier next week when Michael Vick is
expected to play his first regular-season game since Dec. 31,
2006.

The Saints took advantage of a fumble recovery and interception
to turn a four-point halftime lead into a 31-13 advantage in the
first 3 1/2 minutes of the third quarter.

Ellis Hobbs fumbled the second-half kickoff and Chris Reis
recovered at the Eagles 22. Two plays later, Brees tossed an
11-yard TD pass to fullback Heath Evans, who broke a couple
tackles, tiptoed along the sideline and dove over the orange
pylon.

On Philadelphia's next possession, Scott Shanle stepped in front
of Kolb's ill-advised pass to a well-covered Jackson for an easy
pick. Mike Bell ran in from the 7 to make it 31-13.

Jason Avant made a diving catch on fourth-and-goal from the 3 to
cut it to 34-20 late in the third. But Reggie Bush, filling in
for an injured Bell, had a 19-yard TD run to put the Saints
ahead 41-20.

New Orleans needed just two plays to go 54 yards after getting
the ball with 1:20 left in the first half. Bush turned a short
pass into a 29-yard gain, and Brees fired a 25-yard strike to
Marques Colston to give the Saints a 17-10 lead.

Kolb drove Philadelphia 63 yards in 43 seconds, setting up David
Akers' 32-yard field goal before halftime.

The Saints racked up 421 yards against a defense that dominated
the Carolina Panthers in a 38-10 win last week.

"You like starting 2-0, but it doesn't promise you anything,"
Saints coach Sean Payton said.

McNabb got hurt when he was hit hard in the end zone after
scoring on a 3-yard TD run last week against Carolina. He didn't
practice this week and was ruled out 90 minutes before kickoff.

Jeff Garcia, who led the Eagles to a division title and a
playoff win in 2006 after McNabb injured his knee, rejoined the
team Monday as insurance. Vick wasn't eligible to play because
he was suspended for the first two regular-season games as the
final league penalty for his role in running a dogfighting ring.

"It looked like they were clicking on all cylinders at times,
but Donovan is one of the top quarterbacks in the league,"
Sharper said. "He would've made the game look a little
different."

The Eagles allowed a TD on the opening drive for the second
straight week when Brees connected with Colston on a 15-yard
pass.

Kolb hit Jackson in stride with a perfectly thrown deep pass
down the middle and the speedy wideout outraced the defenders
down the sideline to tie the game.

Philadelphia ran nine plays out of the wildcat formation.
Jackson, Westbrook and Jeremy Maclin took snaps. The Eagles
gained 44 yards on seven runs and had two incomplete passes.

"I understand why they did it, but it never allowed (Kolb) to
get in rhythm," Garcia said. "It's a tough game to call. You
have to have some trust and I know the coaches trust him. Just
go out and play football the way we're used to playing."

NOTES: There were a few anti-Vick protesters outside the
stadium. A woman held a sign that read: "Do pitbulls bleed
green?" A young boy carried one that said: "My dog hates Vick."
... Bell left with a knee sprain. He said he could've returned.
... Saints WR Lance Moore left with a hamstring injury. ...
Westbrook sprained his right ankle. ... McNabb has missed 25
games, including playoffs, due to injuries during his 11 seasons
in the NFL. The Eagles are 14-11 in those contests.