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San Francisco 49ers 5-7
Channel: TBD Matchup: TBD Odds: TBD
Buffalo Bills 9-3

San Francisco 49ers @ Buffalo Bills Lines and Odds

  • Betting
  • Scoring
  • Powerline
 
 
474 49ers 5-7-0
458 Bills 9-3-0
Betting
Line SU ATS O/U
5-7 5-7 6-6
9-3 7-5 9-3
Scoring
PPG OPPG
23.75 24
27.75 25.5
Powerline Rating i The Powerline rating compares the current line against a stat-driven estimated line and highlights value opportunities.
Current Estimate Edge
PS ML Team Opp ML PS Score O/U

SF 49ers

  • K'Waun Williams (CB) Week 14 12/08 · Questionable · Ankle
  • Johnathan Cyprien (DB) Cyprien will miss at least three weeks after being placed on IR. 11/15 · Out · Hamstring
  • Ziggy Ansah (DE) Ansah is expected to miss a few games. 10/10 · Out · Biceps
  • Solomon Thomas (DT) Thomas will be out for the season after tearing his ACL. 09/21 · Out · Knee (ACL)
  • George Kittle (TE) Kittle is expected to miss around eight weeks with a fractured bone in his foot. 11/02 · Out · Foot
  • Weston Richburg (C) Richburg will miss several weeks of the 2020 season. 07/28 · Out · Kneecap
  • Jimmy Garoppolo (QB) Garoppolo will miss at least three weeks with a high ankle sprain. 11/02 · Out · Ankle
  • Ronald Blair III (DE) Blair will miss several weeks of the 2020 season. 07/28 · Out · Knee
  • Ken Webster (CB) Webster will miss at least three weeks after being placed on Injured Reserve. 11/30 · Out · Hamstring
  • Kiko Alonso (ILB) The 21-day practice window for Alonso has been activated. 08/01 · Questionable · Knee
  • Nick Bosa (DE) Bosa was injured during Week 2 against the Jets and will miss the remainder of the 2020 season. 09/21 · Out · ACL
  • Dee Ford (DE) Ford will be out for multiple weeks. 10/01 · Out · Back
  • Chris Thompson (WR) Thompson does not have a timetable for his return. 08/16 · Out · Undisclosed
  • JaMycal Hasty (RB) Hasty will miss at least three weeks after being placed on IR. 11/15 · Out · Collarbone
  • Mark Nzeocha (OLB) The 49ers have opened the 21 day window for Nzeocha to return from Injured Reserve. 09/28 · Questionable · Quadriceps
  • Jamar Taylor (CB) Taylor will miss at least three weeks after being placed on Injured Reserve. 11/30 · Out · Knee (ACL)
  • Ben Garland (C) Garland will miss at least a few weeks. 10/19 · Out · Calf
  • Jaquiski Tartt (SS) Tartt will miss at least a few weeks. 11/08 · Out · Toe
  • Jalen Hurd (WR) Hurd has a torn ACL and will miss the 2020 season. 08/17 · Out · Knee
  • D.J. Jones (DT) Week 14 12/08 · Questionable · Ankle
  • Emmanuel Moseley (CB) Week 14 12/08 · Questionable · Hamstring

BUF Bills

  • Jon Feliciano (G) Week 14 12/08 · Questionable · Knee
  • John Brown (WR) Brown is expected to miss a few weeks. 11/16 · Out · Ankle
  • Tyrel Dodson (OLB) Dodson has been designated for return from Injured Reserve as the Bills open the 21-day practice window prior to being activated. 10/19 · Out · Hamstring
  • Cam Lewis (CB) Lewis is expected to miss a few weeks. 10/28 · Out · Wrist
  • Cody Ford (OT) Ford is out for the season. 11/09 · Out · Knee
  • Isaiah Hodgins (WR) Hodgins will miss the first few weeks of the regular season. 09/07 · Out · Shoulder
  • Dane Jackson (CB) Week 13 11/30 · Questionable · Knee
  • Del'Shawn Phillips (OLB) Phillips will miss at least a few weeks. 11/11 · Out · Quadriceps
  • Tommy Sweeney (TE) Sweeney is expected to miss a few weeks. 11/12 · Out · Foot